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Oral antibiotics relieve allergic asthma in post-weaning mice via reducing iNKT cells and function of ADRB2

The role of normal gut microbiota in asthma or ovalbumin (OVA)-induced asthma tolerance (OT) remains unclear. Here, we established mouse models of asthma and OT followed by 2 weeks of antibiotic treatment, to clear the gut microbiota. Antibiotic treatment was found to alleviate allergic asthma accom...

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Detalles Bibliográficos
Autores principales: Li, Na, Chen, Jie, Xie, Sitao, Zhang, Meng, Shi, Tianyun, He, Yanchao, Jie, Zhijun, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640740/
https://www.ncbi.nlm.nih.gov/pubmed/36389706
http://dx.doi.org/10.3389/fimmu.2022.1024235