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Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction

Ras-related protein Rab-20 (Rab20) is induced in hypoxia and contributes to hypoxia-induced apoptosis. However, the role and mechanism of Rab20 in cerebral ischemia/reperfusion (I/R) injury need to be elucidated. We established a cerebral I/R injury model in the mice and an oxygen-glucose deprivatio...

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Detalles Bibliográficos
Autores principales: Guo, Jia, Zhang, Lu, Bu, Yujie, Li, Wenjuan, Hu, Jianping, Li, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640763/
https://www.ncbi.nlm.nih.gov/pubmed/36385754
http://dx.doi.org/10.3389/fnmol.2022.986710