Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly

The inflammasome is a multiprotein complex that triggers the activation of proinflammatory cytokines. The adapter ASC and its isoform ASCb mediate inflammasome assembly via self-association and oligomerization with other inflammasome proteins by homotypic interactions of their two identical Death Do...

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Detalles Bibliográficos
Autores principales: Diaz-Parga, Pedro, Gould, Andrea, de Alba, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640978/
https://www.ncbi.nlm.nih.gov/pubmed/36116550
http://dx.doi.org/10.1016/j.jbc.2022.102501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640978/
https://www.ncbi.nlm.nih.gov/pubmed/36116550
http://dx.doi.org/10.1016/j.jbc.2022.102501

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