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Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly
The inflammasome is a multiprotein complex that triggers the activation of proinflammatory cytokines. The adapter ASC and its isoform ASCb mediate inflammasome assembly via self-association and oligomerization with other inflammasome proteins by homotypic interactions of their two identical Death Do...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640978/ https://www.ncbi.nlm.nih.gov/pubmed/36116550 http://dx.doi.org/10.1016/j.jbc.2022.102501 |