Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway

Aberrant activation of the Wnt/β-catenin signaling pathway is implicated in most malignant cancers, especially in the initiation and progression of colorectal cancer (CRC). DKK4 is a classical inhibitory molecule of the Wnt/β-catenin pathway, but its role in CRC is ambiguous, and the molecular mecha...

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Detalles Bibliográficos
Autores principales: Liang, Junrong, Sun, Lina, Li, Yujun, Liu, Wanning, Li, Danxiu, Chen, Ping, Wang, Xin, Hui, Juan, Zhou, Jinchi, Liu, Hao, Cao, Tianyu, Pang, Maogui, Guo, Meng, Zhao, Xiaodi, Lu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640985/
https://www.ncbi.nlm.nih.gov/pubmed/36181792
http://dx.doi.org/10.1016/j.jbc.2022.102545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640985/
https://www.ncbi.nlm.nih.gov/pubmed/36181792
http://dx.doi.org/10.1016/j.jbc.2022.102545

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