Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatment with Polygonum capitatum Buch.-Ham. ex D. Don extracts

Background: Combination of Polygonum capitatum Buch.-Ham. ex D. Don extract (PCE) and ciprofloxacin (CIP) was commonly prescribed in the treatment of urinary tract infections. Their pharmacokinetic herb-drug interactions (HDIs) were focused in this study to assess potential impact on the safety and...

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Detalles Bibliográficos
Autores principales: Li, Ziqiang, Du, Xi, Tian, Shuang, Fan, Shanshan, Zuo, Xurui, Li, Yanfen, Wang, Ruihua, Wang, Baohe, Huang, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640990/
https://www.ncbi.nlm.nih.gov/pubmed/36386188
http://dx.doi.org/10.3389/fphar.2022.1033667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640990/
https://www.ncbi.nlm.nih.gov/pubmed/36386188
http://dx.doi.org/10.3389/fphar.2022.1033667

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