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Diagnostic accuracy of circulating free DNA testing for the detection of KRAS mutations in non-small cell lung cancer: A systematic review and meta-analysis

Kirsten rat sarcoma viral oncogene homolog (KRAS) gene encodes a GTPase that acts as a molecular switch for intracellular signal transduction, promoting cell growth and proliferation. Mutations in the KRAS gene represent important biomarkers for NSCLC targeted therapy. However, detection of KRAS mut...

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Detalles Bibliográficos
Autores principales: Palmieri, Maria, Zulato, Elisabetta, Wahl, Sissel Gyrid Freim, Guibert, Nicolas, Frullanti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640997/
https://www.ncbi.nlm.nih.gov/pubmed/36386815
http://dx.doi.org/10.3389/fgene.2022.1015161