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An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells

We present an optimized protocol for guided differentiation of retinal pigment epithelium (RPE) cells from human-induced pluripotent stem cells (iPSC). De novo-generated RPE cells are mature, polarized, and mimic the cellular and molecular profile of primary RPE; they are also suitable for in vivo c...

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Detalles Bibliográficos
Autores principales: Surendran, Harshini, Soundararajan, Lalitha, Reddy K, Vijay Bhaskar, Subramani, Janavi, Stoddard, Jonathan, Reynaga, Rene, Tschetter, Wayne, Ryals, Renee C., Pal, Rajarshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641055/
https://www.ncbi.nlm.nih.gov/pubmed/36386870
http://dx.doi.org/10.1016/j.xpro.2022.101803