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An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells
We present an optimized protocol for guided differentiation of retinal pigment epithelium (RPE) cells from human-induced pluripotent stem cells (iPSC). De novo-generated RPE cells are mature, polarized, and mimic the cellular and molecular profile of primary RPE; they are also suitable for in vivo c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641055/ https://www.ncbi.nlm.nih.gov/pubmed/36386870 http://dx.doi.org/10.1016/j.xpro.2022.101803 |