Cargando…

Endothelial SIRT-1 has a critical role in the maintenance of capillarization in brown adipose tissue

Brown adipose tissue (BAT) has critical roles in thermogenesis and systemic metabolism. Capillary rarefaction was reported to develop in BAT with dietary obesity, and previous studies showed that suppression of vascular endothelial growth factor A (VEGF-A) reduced capillary density in BAT, promoting...

Descripción completa

Detalles Bibliográficos
Autores principales: Furuuchi, Ryo, Shimizu, Ippei, Yoshida, Yohko, Katsuumi, Goro, Suda, Masayoshi, Kubota, Yoshiaki, Walsh, Kenneth, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641227/
https://www.ncbi.nlm.nih.gov/pubmed/36388988
http://dx.doi.org/10.1016/j.isci.2022.105424