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Endothelial SIRT-1 has a critical role in the maintenance of capillarization in brown adipose tissue
Brown adipose tissue (BAT) has critical roles in thermogenesis and systemic metabolism. Capillary rarefaction was reported to develop in BAT with dietary obesity, and previous studies showed that suppression of vascular endothelial growth factor A (VEGF-A) reduced capillary density in BAT, promoting...
Autores principales: | Furuuchi, Ryo, Shimizu, Ippei, Yoshida, Yohko, Katsuumi, Goro, Suda, Masayoshi, Kubota, Yoshiaki, Walsh, Kenneth, Minamino, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641227/ https://www.ncbi.nlm.nih.gov/pubmed/36388988 http://dx.doi.org/10.1016/j.isci.2022.105424 |
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