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NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations

Limited therapeutic efficacy and severe side effects represent the central hurdles facing cancer chemotherapy. Immune suppression within tumor immune microenvironments (TIME) has been implicated in chemoresistance. In this study, using a TIME-enabling model system (TIME-EMS), we demonstrate that the...

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Detalles Bibliográficos
Autores principales: Le, Yi, Gao, Hong, Zhu, Angie, Felt, Kristen, Rodig, Scott, Bleday, Ronald, Zhu, Zhenglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641229/
https://www.ncbi.nlm.nih.gov/pubmed/36388981
http://dx.doi.org/10.1016/j.isci.2022.105426