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Prolactin promotes proliferation of germinal center B cells, formation of plasma cells, and elevated levels of IgG3 anti-dsDNA autoantibodies

Systemic lupus erythematosus (SLE) mainly affects females at reproductive age, which has been associated with hormones, such as prolactin (PRL). Different studies suggest that PRL exacerbates the clinical manifestations of SLE both in patients and in mouse models (e.g., the MRL/lpr strain), increasi...

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Detalles Bibliográficos
Autores principales: Carreón-Talavera, Ricardo, Santana-Sánchez, Paola, Fuentes-Pananá, Ezequiel Moisés, Legorreta-Haquet, María Victoria, Chávez-Sánchez, Luis, Gorocica-Rosete, Patricia Sofia, Chávez-Rueda, Adriana Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641231/
https://www.ncbi.nlm.nih.gov/pubmed/36389691
http://dx.doi.org/10.3389/fimmu.2022.1017115