Cargando…
Prolactin promotes proliferation of germinal center B cells, formation of plasma cells, and elevated levels of IgG3 anti-dsDNA autoantibodies
Systemic lupus erythematosus (SLE) mainly affects females at reproductive age, which has been associated with hormones, such as prolactin (PRL). Different studies suggest that PRL exacerbates the clinical manifestations of SLE both in patients and in mouse models (e.g., the MRL/lpr strain), increasi...
Autores principales: | Carreón-Talavera, Ricardo, Santana-Sánchez, Paola, Fuentes-Pananá, Ezequiel Moisés, Legorreta-Haquet, María Victoria, Chávez-Sánchez, Luis, Gorocica-Rosete, Patricia Sofia, Chávez-Rueda, Adriana Karina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641231/ https://www.ncbi.nlm.nih.gov/pubmed/36389691 http://dx.doi.org/10.3389/fimmu.2022.1017115 |
Ejemplares similares
-
Prolactin Increases the Frequency of Follicular T Helper Cells with Enhanced IL21 Secretion and OX40 Expression in Lupus-Prone MRL/lpr Mice
por: Alemán-García, Yolanda P., et al.
Publicado: (2021) -
The effect of prolactin on immune cell subsets involved in SLE pathogenesis
por: Legorreta-Haquet, Maria Victoria, et al.
Publicado: (2022) -
Prolactin Rescues Immature B-Cells from Apoptosis Induced by B-Cell Receptor Cross-Linking
por: Flores-Fernández, Rocio, et al.
Publicado: (2016) -
Prolactin Levels Correlate with Abnormal B Cell Maturation in MRL and MRL/lpr Mouse Models of Systemic Lupus Erythematosus-Like Disease
por: Legorreta-Haquet, Maria Victoria, et al.
Publicado: (2013) -
Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment
por: Ledesma-Soto, Yadira, et al.
Publicado: (2012)