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The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination

During meiosis, programmed DNA double-strand breaks (DSBs) are repaired by homologous recombination. DMC1, a conserved recombinase, plays a central role in this process. DMC1 promotes DNA strand exchange between homologous chromosomes, thus creating the physical linkage between them. Its function is...

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Detalles Bibliográficos
Autores principales: Altmannova, Veronika, Spirek, Mario, Orlic, Lucija, Jēkabsons, Atis, Clarence, Tereza, Henggeler, Adrian, Mlcouskova, Jarmila, Chaleil, Raphaël A.G., Matos, Joao, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641244/
https://www.ncbi.nlm.nih.gov/pubmed/36388968
http://dx.doi.org/10.1016/j.isci.2022.105439