Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner

Mechanisms of cancer cell recognition and elimination by the innate immune system remains unclear. The immune signaling pathways are activated in the fat body to suppress the tumor growth in mxc(mbn1) hematopoietic tumor mutants in Drosophila by inducing antimicrobial peptides (AMP). Here, we invest...

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Detalles Bibliográficos
Autores principales: Kinoshita, Suzuko, Takarada, Kazuki, Kinoshita, Yuriko, Inoue, Yoshihiro H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641529/
https://www.ncbi.nlm.nih.gov/pubmed/36226812
http://dx.doi.org/10.1242/bio.059523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641529/
https://www.ncbi.nlm.nih.gov/pubmed/36226812
http://dx.doi.org/10.1242/bio.059523

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