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Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner
Mechanisms of cancer cell recognition and elimination by the innate immune system remains unclear. The immune signaling pathways are activated in the fat body to suppress the tumor growth in mxc(mbn1) hematopoietic tumor mutants in Drosophila by inducing antimicrobial peptides (AMP). Here, we invest...
Autores principales: | Kinoshita, Suzuko, Takarada, Kazuki, Kinoshita, Yuriko, Inoue, Yoshihiro H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641529/ https://www.ncbi.nlm.nih.gov/pubmed/36226812 http://dx.doi.org/10.1242/bio.059523 |
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