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Validation of atovaquone plasma levels by liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring in pediatric patients

BACKGROUND: Atovaquone has traditionally been used as an antiparasitic and antifungal agent, but recent studies have shown its potential as an anticancer agent. The high variability in atovaquone bioavailability highlights the need for therapeutic drug monitoring, especially in pediatric patients. T...

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Detalles Bibliográficos
Autores principales: Horvath, Thomas D., Poventud-Fuentes, Izmarie, Olayinka, Lily, James, Asha, Haidacher, Sigmund J., Hoch, Kathleen M., Stevens, Alexandra M., Haag, Anthony M., Devaraj, Sridevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641598/
https://www.ncbi.nlm.nih.gov/pubmed/36388060
http://dx.doi.org/10.1016/j.jmsacl.2022.09.004