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Validation of atovaquone plasma levels by liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring in pediatric patients
BACKGROUND: Atovaquone has traditionally been used as an antiparasitic and antifungal agent, but recent studies have shown its potential as an anticancer agent. The high variability in atovaquone bioavailability highlights the need for therapeutic drug monitoring, especially in pediatric patients. T...
Autores principales: | Horvath, Thomas D., Poventud-Fuentes, Izmarie, Olayinka, Lily, James, Asha, Haidacher, Sigmund J., Hoch, Kathleen M., Stevens, Alexandra M., Haag, Anthony M., Devaraj, Sridevi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641598/ https://www.ncbi.nlm.nih.gov/pubmed/36388060 http://dx.doi.org/10.1016/j.jmsacl.2022.09.004 |
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