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Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy

BACKGROUND: While prior research has shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could elucidate important aspects of malaria biology and facilita...

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Detalles Bibliográficos
Autores principales: KC, Natasha, Church, L. W. Preston, Riyahi, Pouria, Chakravarty, Sumana, Seder, Robert A., Epstein, Judith E., Lyke, Kirsten E., Mordmüller, Benjamin, Kremsner, Peter G., Sissoko, Mahamadou S., Healy, Sara, Duffy, Patrick E., Jongo, Said A., Nchama, Vicente Urbano Nsue Ndong, Abdulla, Salim, Mpina, Maxmillian, Sirima, Sodiomon B., Laurens, Matthew B., Steinhardt, Laura C., Oneko, Martina, Li, MingLin, Murshedkar, Tooba, Billingsley, Peter F., Sim, B. Kim Lee, Richie, Thomas L., Hoffman, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641621/
https://www.ncbi.nlm.nih.gov/pubmed/36389797
http://dx.doi.org/10.3389/fimmu.2022.1006716