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Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain

Retrotransposon Gag-like 5 [RTL5, also known as sushi-ichi-related retrotransposon homolog 8 (SIRH8)] and RTL6 (also known as SIRH3) are eutherian-specific genes presumably derived from a retrovirus and phylogenetically related to each other. They, respectively, encode a strongly acidic and extremel...

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Detalles Bibliográficos
Autores principales: Irie, Masahito, Itoh, Johbu, Matsuzawa, Ayumi, Ikawa, Masahito, Kiyonari, Hiroshi, Kihara, Miho, Suzuki, Toru, Hiraoka, Yuichi, Ishino, Fumitoshi, Kaneko-Ishino, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641642/
https://www.ncbi.nlm.nih.gov/pubmed/36162816
http://dx.doi.org/10.1242/dev.200976