A Halogen-Atom Transfer (XAT)-Based Approach to Indole Synthesis Using Aryl Diazonium Salts and Alkyl Iodides

[Image: see text] Indoles are among the most important N-heterocycles in pharmaceuticals. Here, we present an alternative to the classic Fischer indole synthesis based on the radical coupling between aryl diazoniums and alkyl iodides. This iron-mediated strategy features a double role for the aryl d...

Descripción completa

Detalles Bibliográficos
Autores principales: Govaerts, Sebastian, Nakamura, Kento, Constantin, Timothée, Leonori, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641658/
https://www.ncbi.nlm.nih.gov/pubmed/36268790
http://dx.doi.org/10.1021/acs.orglett.2c02840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641658/
https://www.ncbi.nlm.nih.gov/pubmed/36268790
http://dx.doi.org/10.1021/acs.orglett.2c02840

Ejemplares similares