Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction

[Image: see text] A library of thiazoles and selenothiazoles were synthesized via Ir-catalyzed ylide insertion chemistry. This process is a functional group, particularly heterocycle-substituent tolerant. This was applied to the synthesis of fanetizole, an anti-inflammatory drug, and a thiazole-cont...

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Detalles Bibliográficos
Autores principales: Hassell-Hart, Storm, Speranzini, Elisa, Srikwanjai, Sirihathai, Hossack, Euan, Roe, S. Mark, Fearon, Daren, Akinbosede, Daniel, Hare, Stephen, Spencer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641659/
https://www.ncbi.nlm.nih.gov/pubmed/36265082
http://dx.doi.org/10.1021/acs.orglett.2c02996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641659/
https://www.ncbi.nlm.nih.gov/pubmed/36265082
http://dx.doi.org/10.1021/acs.orglett.2c02996

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