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Sequential and additive expression of miR-9 precursors control timing of neurogenesis

MicroRNAs (miRs) have an important role in tuning dynamic gene expression. However, the mechanism by which they are quantitatively controlled is unknown. We show that the amount of mature miR-9, a key regulator of neuronal development, increases during zebrafish neurogenesis in a sharp stepwise mann...

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Detalles Bibliográficos
Autores principales: Soto, Ximena, Burton, Joshua, Manning, Cerys S., Minchington, Thomas, Lea, Robert, Lee, Jessica, Kursawe, Jochen, Rattray, Magnus, Papalopulu, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641661/
https://www.ncbi.nlm.nih.gov/pubmed/36189829
http://dx.doi.org/10.1242/dev.200474