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Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism

Nephron endowment is defined by fetal kidney growth and crucially dictates renal health in adults. Defects in the molecular regulation of nephron progenitors contribute to only a fraction of reduced nephron mass cases, suggesting alternative causative mechanisms. The importance of MAPK/ERK activatio...

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Detalles Bibliográficos
Autores principales: Kwon, Hyuk Nam, Kurtzeborn, Kristen, Iaroshenko, Vladislav, Jin, Xing, Loh, Abigail, Escande-Beillard, Nathalie, Reversade, Bruno, Park, Sunghyouk, Kuure, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641663/
https://www.ncbi.nlm.nih.gov/pubmed/36189831
http://dx.doi.org/10.1242/dev.200986