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Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism
Nephron endowment is defined by fetal kidney growth and crucially dictates renal health in adults. Defects in the molecular regulation of nephron progenitors contribute to only a fraction of reduced nephron mass cases, suggesting alternative causative mechanisms. The importance of MAPK/ERK activatio...
Autores principales: | Kwon, Hyuk Nam, Kurtzeborn, Kristen, Iaroshenko, Vladislav, Jin, Xing, Loh, Abigail, Escande-Beillard, Nathalie, Reversade, Bruno, Park, Sunghyouk, Kuure, Satu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641663/ https://www.ncbi.nlm.nih.gov/pubmed/36189831 http://dx.doi.org/10.1242/dev.200986 |
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