Identification of a novel specific small-molecule melanocortin-2-receptor antagonist

The overproduction of adrenocorticotropic hormone (ACTH), in conditions such as Cushing’s disease and congenital adrenal hyperplasia (CAH), leads to significant morbidity. Current treatment with glucocorticoids does not adequately suppress plasma ACTH, resulting in excess adrenal androgen production...

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Detalles Bibliográficos
Autores principales: Forfar, Rachel, Hussain, Mashal, Khurana, Puneet, Cook, Jennifer, Lewis, Steve, Popat, Dillon, Jackson, David, McIver, Ed, Jerman, Jeff, Taylor, Debra, Clark, Adrian JL, Chan, Li F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641778/
https://www.ncbi.nlm.nih.gov/pubmed/36515667
http://dx.doi.org/10.1530/EC-22-0338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641778/
https://www.ncbi.nlm.nih.gov/pubmed/36515667
http://dx.doi.org/10.1530/EC-22-0338

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