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Identification of a novel specific small-molecule melanocortin-2-receptor antagonist
The overproduction of adrenocorticotropic hormone (ACTH), in conditions such as Cushing’s disease and congenital adrenal hyperplasia (CAH), leads to significant morbidity. Current treatment with glucocorticoids does not adequately suppress plasma ACTH, resulting in excess adrenal androgen production...
Autores principales: | Forfar, Rachel, Hussain, Mashal, Khurana, Puneet, Cook, Jennifer, Lewis, Steve, Popat, Dillon, Jackson, David, McIver, Ed, Jerman, Jeff, Taylor, Debra, Clark, Adrian JL, Chan, Li F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641778/ https://www.ncbi.nlm.nih.gov/pubmed/36515667 http://dx.doi.org/10.1530/EC-22-0338 |
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