Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study

Telomere length (TL) is associated with biological aging, consequently influencing the risk of age-related diseases such as Alzheimer’s disease (AD). We aimed to evaluate the potential causal role of TL in AD endophenotypes (i.e., cognitive performance, N = 2233; brain age and AD-related signatures,...

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Detalles Bibliográficos
Autores principales: Rodríguez-Fernández, Blanca, Vilor-Tejedor, Natalia, Arenaza-Urquijo, Eider M., Sánchez-Benavides, Gonzalo, Suárez-Calvet, Marc, Operto, Grégory, Minguillón, Carolina, Fauria, Karine, Kollmorgen, Gwendlyn, Suridjan, Ivonne, de Moura, Manuel Castro, Piñeyro, David, Esteller, Manel, Blennow, Kaj, Zetterberg, Henrik, De Vivo, Immaculata, Molinuevo, José Luis, Navarro, Arcadi, Gispert, Juan Domingo, Sala-Vila, Aleix, Crous-Bou, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641781/
https://www.ncbi.nlm.nih.gov/pubmed/36345036
http://dx.doi.org/10.1186/s13195-022-01101-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641781/
https://www.ncbi.nlm.nih.gov/pubmed/36345036
http://dx.doi.org/10.1186/s13195-022-01101-9

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