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An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation

BACKGROUND: Semaphorins (Sema) belong to a large family of repellent guidance cues instrumental in guiding axons during development. In particular, Class 3 Sema (Sema 3) is among the best characterized Sema family members and the only produced as secreted proteins in mammals, thereby exerting both a...

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Detalles Bibliográficos
Autores principales: Ferretti, Gabriella, Romano, Alessia, Sirabella, Rossana, Serafini, Sara, Maier, Thorsten Jürgen, Matrone, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641809/
https://www.ncbi.nlm.nih.gov/pubmed/36348448
http://dx.doi.org/10.1186/s13578-022-00916-1