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Differential properties of KRAS transversion and transition mutations in non-small cell lung cancer: associations with environmental factors and clinical outcomes

BACKGROUND: KRAS-mutated non-small cell lung cancer (NSCLC) accounts for 23–35% and 13–20% of all NSCLCs in white patients and East Asians, respectively, and is therefore regarded as a major therapeutic target. However, its epidemiology and clinical characteristics have not been fully elucidated bec...

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Detalles Bibliográficos
Autores principales: Sato, Koichi, Akamatsu, Hiroaki, Koh, Yasuhiro, Ogawa, Koichi, Isa, Shun-ichi, Ando, Masahiko, Tamiya, Akihiro, Kubo, Akihito, Kitagawa, Chiyoe, Kawaguchi, Tomoya, Yamamoto, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641926/
https://www.ncbi.nlm.nih.gov/pubmed/36348317
http://dx.doi.org/10.1186/s12885-022-10246-7