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A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

BACKGROUND: The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer similarity to humans in these aspects, compared to the widely u...

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Detalles Bibliográficos
Autores principales: Toh, Huishi, Yang, Chentao, Formenti, Giulio, Raja, Kalpana, Yan, Lily, Tracey, Alan, Chow, William, Howe, Kerstin, Bergeron, Lucie A., Zhang, Guojie, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Fogg, John, Kirilenko, Bogdan, Munegowda, Chetan, Hiller, Michael, Jain, Aashish, Kihara, Daisuke, Rhie, Arang, Phillippy, Adam M., Swanson, Scott A., Jiang, Peng, Clegg, Dennis O., Jarvis, Erich D., Thomson, James A., Stewart, Ron, Chaisson, Mark J. P., Bukhman, Yury V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641963/
https://www.ncbi.nlm.nih.gov/pubmed/36344967
http://dx.doi.org/10.1186/s12915-022-01427-8