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Early Nitrogenase Ancestors Encompassed Novel Active Site Diversity

Ancestral sequence reconstruction (ASR) infers predicted ancestral states for sites within sequences and can constrain the functions and properties of ancestors of extant protein families. Here, we compare the likely sequences of inferred nitrogenase ancestors to extant nitrogenase sequence diversit...

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Detalles Bibliográficos
Autores principales: Schwartz, Sarah L, Garcia, Amanda K, Kaçar, Betül, Fournier, Gregory P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641968/
https://www.ncbi.nlm.nih.gov/pubmed/36260513
http://dx.doi.org/10.1093/molbev/msac226