Innate immune mechanisms of mRNA vaccines

The lipid nanoparticle (LNP)-encapsulated, nucleoside-modified mRNA platform has been used to generate safe and effective vaccines in record time against COVID-19. Here, we review the current understanding of the manner whereby mRNA vaccines induce innate immune activation and how this contributes t...

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Detalles Bibliográficos
Autores principales: Verbeke, Rein, Hogan, Michael J., Loré, Karin, Pardi, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641982/
https://www.ncbi.nlm.nih.gov/pubmed/36351374
http://dx.doi.org/10.1016/j.immuni.2022.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641982/
https://www.ncbi.nlm.nih.gov/pubmed/36351374
http://dx.doi.org/10.1016/j.immuni.2022.10.014

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