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Innate immune mechanisms of mRNA vaccines
The lipid nanoparticle (LNP)-encapsulated, nucleoside-modified mRNA platform has been used to generate safe and effective vaccines in record time against COVID-19. Here, we review the current understanding of the manner whereby mRNA vaccines induce innate immune activation and how this contributes t...
Autores principales: | Verbeke, Rein, Hogan, Michael J., Loré, Karin, Pardi, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641982/ https://www.ncbi.nlm.nih.gov/pubmed/36351374 http://dx.doi.org/10.1016/j.immuni.2022.10.014 |
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