Cargando…
General Theory of Specific Binding: Insights from a Genetic-Mechano-Chemical Protein Model
Proteins need to selectively interact with specific targets among a multitude of similar molecules in the cell. However, despite a firm physical understanding of binding interactions, we lack a general theory of how proteins evolve high specificity. Here, we present such a model that combines chemis...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641994/ https://www.ncbi.nlm.nih.gov/pubmed/36208205 http://dx.doi.org/10.1093/molbev/msac217 |