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Mode and Tempo of 3D Genome Evolution in Drosophila

Topologically associating domains (TADs) are thought to play an important role in preventing gene misexpression by spatially constraining enhancer–promoter contacts. The deleterious nature of gene misexpression implies that TADs should, therefore, be conserved among related species. Several early st...

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Detalles Bibliográficos
Autores principales: Torosin, Nicole S, Golla, Tirupathi Rao, Lawlor, Matthew A, Cao, Weihuan, Ellison, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641997/
https://www.ncbi.nlm.nih.gov/pubmed/36201625
http://dx.doi.org/10.1093/molbev/msac216