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Cryomicroscopy in situ: what is the smallest molecule that can be directly identified without labels in a cell?
Electron cryomicroscopy (cryoEM) has made great strides in the last decade, such that the atomic structure of most biological macromolecules can, at least in principle, be determined. Major technological advances – in electron imaging hardware, data analysis software, and cryogenic specimen preparat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642008/ https://www.ncbi.nlm.nih.gov/pubmed/35913392 http://dx.doi.org/10.1039/d2fd00076h |