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Cryomicroscopy in situ: what is the smallest molecule that can be directly identified without labels in a cell?

Electron cryomicroscopy (cryoEM) has made great strides in the last decade, such that the atomic structure of most biological macromolecules can, at least in principle, be determined. Major technological advances – in electron imaging hardware, data analysis software, and cryogenic specimen preparat...

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Detalles Bibliográficos
Autores principales: Russo, Christopher J., Dickerson, Joshua L., Naydenova, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642008/
https://www.ncbi.nlm.nih.gov/pubmed/35913392
http://dx.doi.org/10.1039/d2fd00076h