The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease

Androgen receptor (AR) is a key member of nuclear hormone receptors with the longest intrinsically disordered N-terminal domain (NTD) in its protein family. There are four mono-amino acid repeats (polyQ1, polyQ2, polyG, and polyP) located within its NTD, of which two are polymorphic (polyQ1 and poly...

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Detalles Bibliográficos
Autores principales: Meszaros, Attila, Ahmed, Junaid, Russo, Giorgio, Tompa, Peter, Lazar, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642029/
https://www.ncbi.nlm.nih.gov/pubmed/36388907
http://dx.doi.org/10.3389/fmed.2022.1019803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642029/
https://www.ncbi.nlm.nih.gov/pubmed/36388907
http://dx.doi.org/10.3389/fmed.2022.1019803

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