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The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease
Androgen receptor (AR) is a key member of nuclear hormone receptors with the longest intrinsically disordered N-terminal domain (NTD) in its protein family. There are four mono-amino acid repeats (polyQ1, polyQ2, polyG, and polyP) located within its NTD, of which two are polymorphic (polyQ1 and poly...
Autores principales: | Meszaros, Attila, Ahmed, Junaid, Russo, Giorgio, Tompa, Peter, Lazar, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642029/ https://www.ncbi.nlm.nih.gov/pubmed/36388907 http://dx.doi.org/10.3389/fmed.2022.1019803 |
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