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High-throughput cryo-EM structure determination of amyloids

The formation of amyloid filaments is characteristic of various degenerative diseases. Recent breakthroughs in electron cryo-microscopy (cryo-EM) have led to atomic structure determination of multiple amyloid filaments, both of filaments assembled in vitro from recombinant proteins, and of filaments...

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Detalles Bibliográficos
Autores principales: Lövestam, Sofia, Scheres, Sjors H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642048/
https://www.ncbi.nlm.nih.gov/pubmed/35913272
http://dx.doi.org/10.1039/d2fd00034b