Increased Presynaptic Dopamine Synthesis Capacity Is Associated With Aberrant Dopamine Neuron Activity in the Methylazoxymethanol Acetate Rodent Model Used to Study Schizophrenia-Related Pathologies

Aberrant dopamine system function is thought to contribute to the positive symptoms of schizophrenia. Clinical imaging studies have demonstrated that the largest dopamine abnormality in patients appears to be an increase in presynaptic dopamine activity. Indeed, studies utilizing [(18)F]DOPA positiv...

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Detalles Bibliográficos
Autores principales: Perez, Stephanie M, Elam, Hannah B, Lodge, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642313/
https://www.ncbi.nlm.nih.gov/pubmed/36387971
http://dx.doi.org/10.1093/schizbullopen/sgac067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642313/
https://www.ncbi.nlm.nih.gov/pubmed/36387971
http://dx.doi.org/10.1093/schizbullopen/sgac067

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