Targeting mTOR Complex 2 in Castration-Resistant Prostate Cancer with Acquired Docetaxel Resistance

PURPOSE: Mammalian Target of rapamycin (mTOR) plays a central role in regulating cell growth, proliferation, and cell cycle. The key component of mTORC2 is highly expressed in docetaxel-resistant prostate cells. However, the underlying molecular effects on prostate cells remain unclear. METHODS: A d...

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Detalles Bibliográficos
Autores principales: Huang, Yujie, Zhai, You, Wu, Meijia, Chang, Chengdong, Luo, Jindan, Hong, Dongsheng, Zhao, Qingwei, Dai, Yao, Liu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642805/
https://www.ncbi.nlm.nih.gov/pubmed/36388085
http://dx.doi.org/10.2147/DDDT.S376474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642805/
https://www.ncbi.nlm.nih.gov/pubmed/36388085
http://dx.doi.org/10.2147/DDDT.S376474

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