Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress

Oxidative stress is a major risk factor that causes osteocyte cell death and bone loss. Prior studies primarily focus on the function of cell surface expressed Cx43 channels. Here, we reported a new role of mitochondrial Cx43 (mtCx43) and hemichannels (HCs) in modulating mitochondria homeostasis and...

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Detalles Bibliográficos
Autores principales: Zhang, Jingruo, Riquelme, Manuel A, Hua, Rui, Acosta, Francisca M, Gu, Sumin, Jiang, Jean X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642995/
https://www.ncbi.nlm.nih.gov/pubmed/36346745
http://dx.doi.org/10.7554/eLife.82206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642995/
https://www.ncbi.nlm.nih.gov/pubmed/36346745
http://dx.doi.org/10.7554/eLife.82206

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