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HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway

BACKGROUND: HIV infection dysregulates the B cell compartment, affecting memory B cell formation and the antibody response to infection and vaccination. Understanding the B cell response to SARS-CoV-2 in people living with HIV (PLWH) may explain the increased morbidity, reduced vaccine efficacy, red...

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Detalles Bibliográficos
Autores principales: Krause, Robert, Snyman, Jumari, Shi-Hsia, Hwa, Muema, Daniel, Karim, Farina, Ganga, Yashica, Ngoepe, Abigail, Zungu, Yenzekile, Gazy, Inbal, Bernstein, Mallory, Khan, Khadija, Mazibuko, Matilda, Mthabela, Ntombifuthi, Ramjit, Dirhona, Limbo, Oliver, Jardine, Joseph, Sok, Devin, Wilson, Ian A, Hanekom, Willem, Sigal, Alex, Kløverpris, Henrik, Ndung'u, Thumbi, Leslie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643005/
https://www.ncbi.nlm.nih.gov/pubmed/36300787
http://dx.doi.org/10.7554/eLife.79924