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Routes of administration for adeno-associated viruses carrying gene therapies for brain diseases

Gene therapy is a powerful tool to treat various central nervous system (CNS) diseases ranging from monogenetic diseases to neurodegenerative disorders. Adeno-associated viruses (AAVs) have been widely used as the delivery vehicles for CNS gene therapies due to their safety, CNS tropism, and long-te...

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Detalles Bibliográficos
Autores principales: Zhou, Kai, Han, Jinming, Wang, Yafeng, Zhang, Yaodong, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643316/
https://www.ncbi.nlm.nih.gov/pubmed/36385771
http://dx.doi.org/10.3389/fnmol.2022.988914