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Antibody-dependent cellular cytotoxicity-null effector developed using mammalian and plant GlycoDelete platform

Cancer therapy using immune checkpoint inhibitor antibodies has markedly shifted the paradigm of cancer treatment. However, methods completely eliminating the effector function of these signal-regulating antibodies is urgently required. The heterogeneity of glycan chains in antibodies limits their u...

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Detalles Bibliográficos
Autores principales: Kang, Cho Eun, Lee, Seungeun, Ahn, Taeyoung, Seo, Dong Hye, Ko, Byoung Joon, Jung, Minkyu, Lee, Jinu, Kim, Joo Young, Kim, Woo Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643331/
https://www.ncbi.nlm.nih.gov/pubmed/36347901
http://dx.doi.org/10.1038/s41598-022-23311-9