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Antibody-dependent cellular cytotoxicity-null effector developed using mammalian and plant GlycoDelete platform
Cancer therapy using immune checkpoint inhibitor antibodies has markedly shifted the paradigm of cancer treatment. However, methods completely eliminating the effector function of these signal-regulating antibodies is urgently required. The heterogeneity of glycan chains in antibodies limits their u...
Autores principales: | Kang, Cho Eun, Lee, Seungeun, Ahn, Taeyoung, Seo, Dong Hye, Ko, Byoung Joon, Jung, Minkyu, Lee, Jinu, Kim, Joo Young, Kim, Woo Taek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643331/ https://www.ncbi.nlm.nih.gov/pubmed/36347901 http://dx.doi.org/10.1038/s41598-022-23311-9 |
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