Exosomal protein angiopoietin-like 4 mediated radioresistance of lung cancer by inhibiting ferroptosis under hypoxic microenvironment

BACKGROUND: Hypoxia-mediated radioresistance is a major reason for the adverse radiotherapy outcome of non-small cell lung cancer (NSCLC) in clinical, but the underlying molecular mechanisms are still obscure. METHODS: Cellular and exosomal ANGPTL4 proteins under different oxygen status were examine...

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Detalles Bibliográficos
Autores principales: Zhang, Yuhong, Liu, Xinglong, Zeng, Liang, Zhao, Xinrui, Chen, Qianping, Pan, Yan, Bai, Yang, Shao, Chunlin, Zhang, Jianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643351/
https://www.ncbi.nlm.nih.gov/pubmed/36050447
http://dx.doi.org/10.1038/s41416-022-01956-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643351/
https://www.ncbi.nlm.nih.gov/pubmed/36050447
http://dx.doi.org/10.1038/s41416-022-01956-7

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