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Exosomal protein angiopoietin-like 4 mediated radioresistance of lung cancer by inhibiting ferroptosis under hypoxic microenvironment
BACKGROUND: Hypoxia-mediated radioresistance is a major reason for the adverse radiotherapy outcome of non-small cell lung cancer (NSCLC) in clinical, but the underlying molecular mechanisms are still obscure. METHODS: Cellular and exosomal ANGPTL4 proteins under different oxygen status were examine...
Autores principales: | Zhang, Yuhong, Liu, Xinglong, Zeng, Liang, Zhao, Xinrui, Chen, Qianping, Pan, Yan, Bai, Yang, Shao, Chunlin, Zhang, Jianghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643351/ https://www.ncbi.nlm.nih.gov/pubmed/36050447 http://dx.doi.org/10.1038/s41416-022-01956-7 |
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