GZMK(high) CD8(+) T effector memory cells are associated with CD15(high) neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

CD8(+) T cells are a major prognostic determinant in solid tumors, including colorectal cancer (CRC). However, understanding how the interplay between different immune cells impacts on clinical outcome is still in its infancy. Here, we describe that the interaction of tumor infiltrating neutrophils...

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Detalles Bibliográficos
Autores principales: Tiberti, Silvia, Catozzi, Carlotta, Croci, Ottavio, Ballerini, Mattia, Cagnina, Danilo, Soriani, Chiara, Scirgolea, Caterina, Gong, Zheng, He, Jiatai, Macandog, Angeli D., Nabinejad, Amir, Nava Lauson, Carina B., Quinte’, Arianna, Bertalot, Giovanni, Petz, Wanda L., Ravenda, Simona P., Licursi, Valerio, Paci, Paola, Rasponi, Marco, Rotta, Luca, Fazio, Nicola, Ren, Guangwen, Fumagalli-Romario, Uberto, Schaefer, Martin H., Campaner, Stefano, Lugli, Enrico, Nezi, Luigi, Manzo, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643357/
https://www.ncbi.nlm.nih.gov/pubmed/36347862
http://dx.doi.org/10.1038/s41467-022-34467-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643357/
https://www.ncbi.nlm.nih.gov/pubmed/36347862
http://dx.doi.org/10.1038/s41467-022-34467-3

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